Abstract Intruduction: Ligation of the intersphincteric fistula tract (LIFT) is a new sphincter-sparing procedure for anal fistula. The success rate is comparable with other sphincter-preserving techniques. The objective of the study is to evaluate the results of LIFT in the management of transsphincteric and suprasphincteric anal fistula and to assess any change in continence after the procedure. Methods: One hundred and ten patients with transsphincteric and suprasphincteric anal fistula were included in the study. Assessment of continence and anal manometry were performed before and after the procedure. Primary outcome measure was complete healing. Minimum follow-up was one year following the procedure. Results: Primary healing occurred in 83.63% patients. The average healing time was seven weeks. None of the patients reported any change in continence after the procedure. There was no significant difference in resting and maximal anal pressures before and after the procedure. Conclusion: The results of the LIFT technique are very promising. This technique has the potential to become the gold standard for transsphincteric and suprasphincteric anal fistula.