Introduction: Laparoscopic cholecystectomy is the gold standard procedure for gall stone disease. Few cases of acute calculous cholecystitis require conversion to open procedure. Patients with diabetes and hypertension are at increased risk of failure of laparoscopic cholecystectomy. Aims and Objectives: To evaluate the risk of failure of laparoscopic cholecystectomy in type 2 diabetes patients with patients without diabetes. Materials and methods: A prospective study was conducted at a tertiary care hospital. Study was conducted after obtaining ethical committee clearance and informed consent from patients. 90 patients were included in the study. Results: 90 patients of acute calculous cholecystitis were taken for laparoscopic cholecystectomy of which 38 patients had to undergo conversion to open procedure. Among these 17 where having diabetes and hypertension and 14 had type 2 diabetes alone. Conclusion: It is important to evaluate in detail before taking the patients with commodities like diabetes and hypertension for laparoscopic cholecystectomy and prevent morbidity

. Keywords: Acute calculous cholecystitis; Cholecystectomy; Laparoscopic cholecystectomy; Failure of laparoscopy; Conversion to open cholecystectomy; diabetes with cholecystitis; diabetes and laparoscopic cholecystectomy.