Chemical meningitis is a syndrome characterized by fever and signs of meningism with cerebrospinal fluid (CSF) pleocytosis, increased protein and blood & CSF culture negative. It is a common complication after posterior fossa surgery than the fronto, temporo and parietal craniotomy procedures. It is often self limiting course requiring repeated CSF examination to exclude infection. We report a case of recurrent thalamic pilocytic astrocytoma underwent fronto temporal craniotomy, post operatively developed pseudo meningocele with features of chemical meningitis. As all conservative measures failed, patient underwent Lumboperitoneal shunt, found to be resolution of symptoms.

Keywords: Chemical meningitis, Pseudomeningocele;Lumboperitoneal shunt.