Introduction: The present study was done to compare the diagnostic accuracy of Fine Needle Aspiration Cytology (FNAC) in differentiating the benign and malignant lesions of palpable breast lumps with histopathological correlation and alsoto study the accuracy of FNAC procedure. Materials and Method: A retrospective study was done for a period of one year from January 2017 to January 2018. Fine needle aspiration was carried out in Department of pathology by pathologist, slides were stained with May-grunwald Giemsa morphology was studied, lumpectomy, wide excision and modified radical mastectomies were received depending on diagnosis on cytology. FNAC and biopsy results were correlated. Results: The most common age group for benign lesions were between 11 to 40 years and for the malignant lesion was 41 to 70 years. Fibroadenoma was most common among benign neoplasms and infiltrating ductal carcinoma (IDC) constituted highest number of cases among malignant neoplasms. Total benign cases were 22 and malignant were 11, premalignant (2 fibrocystic disease with atypia and 1 atypical ductal hyperplasia), and granulomatous mastitis were 2 out of total 38 cases. Conclusion: FNAC of the breast lump is an OPD based diagnostic method for determining the nature of the breast lump. It is safe, minimally painful, without anesthesia. Requiring only syringe, needle, glass slides and fixatives. Repeat FNAC can be performed if necessary. Best screening method required for categorization of different lesions of breast which aids in prevention of cancer and proper management of lesions.