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Indian Journal of Pathology: Research and Practice

Volume  7, Issue 8, August 2018, Pages 938-942
 

Original Article

Histopathological Study and P53 Expression of Colonic PolypsHistopathological Study and P53 Expression of Colonic Polyps

Vidhya Subramanian1, Pernati Mahendranath2

1Assistant Professor 2Associate Professor, Department of Pathology, ACS Medical College & Hospital, Chennai, Tamil Nadu 600077, India.

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7818.10

Abstract

Background: Hyperplastic and Adenomatous polyps are most common in large intestine. Morphological study of polyps helps us to know the incidence and malignant transformation of polyps.

Aims and Objectives: To study the incidence and morphology of colonic Polyps.

Materials and Methods: Prospective study, 52 colonic polyps were reported which include both colonoscopic biopsies (polypectomy) and resection specimens.

Observation and Results: The commonest site of involvement was sigmoid colon and the commonest lesion was adenomatous polyps.

Conclusion: Adenomatous polyps are more common in colon and further study are required to know the malignant transformation.

Keywords: FAP-Familial Adenomatous Polyposis; PJ Polyp-Peutz-Jeghers Polyp.


Corresponding Author : Pernati Mahendranath, Associate Professor, Dept. of Pathology, ACS Medical College & Hospital, Chennai, Tamil Nadu 600077, India.