BCG is presently most studied immunostimulating agent which is able to stimulate delayed type of hypersesitivity (DTH) reaction by activating macrophages (Florentin etal 1976) we have taken diagnosed cases of HD (Hodgkin disease), patient from cancer hospital and research institute Gwalior. The studies are carried under the supervision of cancer specialist and clinician for correlation of Results. The beneficial effect was evaluated by observing improved clinical responses with regression of tumor and increase of life span of these patients. These patients were given BCG immunotherapy along with definitive therapy in various combinations. Therefore this study has been under taken with the aim and objectives. 1. To study of immunostimulatory effect of BCG in cases of Hodgkins lymphoma. 2. To evaluate immunotherapy of HD in correlation with clinical stages of disease.

Key words: (HI) Hodgkin’s lymphoma; BCG (Bacillus calmette Guerin).