Context: Eosinophilic enterocolitis is a rare inflammatory disease of unknown origin, characterised by diffuse eosinophilic infiltration of gastrointestinal tract, accompanied by varying abdominal symptoms. The condition is increasing in frequency in recent years and is associated with major complications if untreated. Hence, it is very necessary to diagnose the condition. Hence, the present study was done to evaluate for eosinophilic enterocolitis in intestinal biopsies, and to correlate with peripheral eosinophilia.

Aims: 1. To evaluate intestinal biopsies for eosinophilic enterocolitis. 2. To correlate with peripheral esoinophilia. Settings and Design: All the intestinal biopsies received in the department of Pathology of M.S. Ramaiah Medical College, Bangalore, from November 2015 to November 2016 were evaluated. Specific criteria for diagnosis of eosinophilic enterocolitis was used, criteria being eosinophils ranging from 10-50/HPF in the biopsies. Correlation with peripheral eosinophilia was also done.

Methods and Material: All the intestinal biopsies received in the department of Pathology of M.S. Ramaiah Medical College, Bangalore, from November 2015 to November 2016 were evaluated. Specific criteria for diagnosis of eosinophilic enterocolitis was used, criteria being eosinophils ranging from 10-50/HPF in the biopsies. Correlation with peripheral eosinophilia was also done. Statistical Analysis used: Statistical analysis is not required as it is a analytical study.

Results: A total of 52 cases of intestinal biopsies were obtained during the one year study period. Out of the 52 cases, 5 cases (9.6%) were diagnosed as eosinophilic enterocolitis. Out of the 52 cases, 3 cases (60%) were associated with peripheral eosinophilia. Out of the 5 patients with eosinophilic enterocolitis, 4 were men and only 1 was a woman, 

Conclusions: The incidence of eosinophilic enterocolitis is increasing in recent years. Hence
this condition should be considered in the differential diagnosis whenever a patient presents
with chronic diarrhea. Timely treatment can prevent major complications in these patients.

Keywords: Eosinophilic Enterocolitis; Peripheral Eosinophilia.