Introduction: Metaplastic carcinoma of breast belongs to a diverse class of neoplasm constituting the rarest histological variant of invasive ductal carcinoma. Adenosquamous carcinoma of breast is a rare tumour which is a variant of metaplastic carcinoma, comprising 0.3% of breast carcinomas. Case Report: Here, we report a case of adenosquamous variant of metaplastic carcinoma of breast in a 61 years old female who presented with a lump in the right breast. Conclusion: The present case highlights that although adenosquamous carcinoma of breast is rare, we should be aware of this possibility and include it in the differential diagnosis whenever appropriate.

Keywords: Metaplastic; Adenosquamous; Carcinoma.