Objective: We conducted three years retrospective study in tertiary care hospital in India catering to both urban as well as rural fraternity to see the various pattern of renal diseases. Methods: The present study comprised of studying all the biopsy (core needle as well as nephrectomy) specimens coming to pathology department, GMC Aurangabad. Results: A total of 72 cases over a period of three years were studied. Data in this study showed that non-neoplastic lesions comprised of 48 cases (66.7%) & neoplastic lesions were 24 cases (33.3%). Chronic pyelonephritis predominated in the non-neoplastic group & in the neoplastic group renal cell carcinoma was the commonest. Conclusion: A wide range of lesions are encountered on histopathology, many of which may be misdiagnosed clinically and radiologically; therefore, it is mandatory that every renal biopsy specimen be subjected to detailed histopathological examination for a clinico-morphological correlation to ensure proper management.

Keywords: Renal Diseases; Chronic Pyelonephritis; Renal Cell Carcinoma (RCC)