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Indian Journal of Pathology: Research and Practice

Volume  7, Issue 1, January 2018, Pages 64-70
 

Original Article

Clinico Histopathological Study of Gastrointestinal Polyps: A Prospective Study of 160 Polypectomy Specimens

Muram Reddy Vijaya Lakshmi*, Muram Reddy Penchala Reddy**, Vissa Shanthi***, Nandam Mohan Rao****, Byna Syam Sundara Rao*****, Grandhi Bhavana******

*,**Assistant Professor ***,****Professor *****,******Associate Professor, Department of Pathology, Narayana Medical College, Nellore, Andhra Pradesh 524003, India.

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7118.11

Abstract

Background: Gastrointestinal polyps are proliferative or neoplastic mucosal lesions, projecting into gastrointestinal lumina. Certain polyps like adenomatous polyps have more clinical importance because they have the risk of malignancy. Aim: The aim of our study is to determine the age and sex distribution, location, histological type and also to assess the benign or malignant potential of gastrointestinal polyps. Materials and Methods: This study was done in the Department of Pathology, Narayana Medical College and Hospital, Nellore, Andhra Pradesh, India, over a period of two years from October 2015 to September 2017. Total 160 Cases of Gatrointestinal polyps were studied. Results: Gatrointestinal polyps were more common in males (60%) than females (40%) and were common in the age group between 51-60 years (40%). Commonest clinical symptom was malena (28.12%). Rectum was the commonest site (28.75%), followed by sigmoid colon (18.75%). The most prevalent type of gastrointestinal polyp was adenomatous polyp (50%). The commonest subtype of adenomatous polyp was tubular variant (82.5%). Conclusion: High grades of dysplasia was commonly observed in villous and tubulovillous types of adenomatous polyps. As adenomatous polyps have more risk of malignant transformation, early diagnosis and removal is a highly effective method in preventing colorectal cancer.

Keywords: Adenomatous Polyp; Dysplasia; Gastro Intestinal Polyps; Rectum; Tubular Variant. 


Corresponding Author : Muram Reddy Penchala Reddy, Assistant Professor, Dept. of Pathology, Narayana Medical College, Nellore, Andhra Pradesh 524003, India.