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Indian Journal of Pathology: Research and Practice

Volume  6, Issue 4 (Part-2), Oct-Dec 2017, Pages 1046-1051
 

Original Article

Analysis of Papulosquamous Skin Disorders in Skin Biopsies: A Clinico Histopathological Study

Muram Reddy Vijaya Lakshmi*, Muram Reddy Penchala Reddy*, Vissa Shanthi**, Nandam Mohan Rao***, Byna Syam Sundara Rao***, Grandhi Bhavana***

*Assistant Professor **Professor ***Associate Professor, Dept. of Pathology, Narayana Medical College, Nellore, Andhra Pradesh 524003, India.

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.6417.37

Abstract

Background: Papulosquamous disorders assume considerable importance because of their frequency of occurrence. As all the lesions are characterized by scaling papules and plaques, clinical confusion may occur in their diagnosis and hence these lesions are commonly misdiagnosed. Separation of each of these lesions becomes important because, for each disease, the treatment and prognosis is disease specific. Aim: To analyse various papulosquamous disorders of skin, to study the histopathological features and also to know the correlation between clinical and histopathological diagnosis. Materials and Methods: This study was done in the Department of Pathology, Narayana medical college and hospital, Nellore, Andhrapradesh, India for a period of 1 year from June 2016 to June 2017. Total 108 cases of papulosquamous skin disorders were studied. Results: Psoriasis was the commonest lesion (53.70%), followed by Lichen planus (29.63%), Pityriasis rubra pilaris (7.41%), Lichen nitidus (5.55%) and Parapsoriasis (3.70%). Papulosquamous skin lesions were common in 2140years age group (38.9%). Papulosquamous skin lesions were more common in males, than females with a male:female ratio of 1.7:1. Both age and sex distribution of cases showed significant p value < 0.001. In our study, histopathology confirmed the clinical diagnosis in 42.6% of cases. Histopathology gave the diagnosis when differential diagnosis were there in 51.85% of cases and in 5.55% of cases, histopathological diagnosis was different from clinical diagnosis. Conclusion: Our study concludes that histopathology is the gold standard investigation for diagnosis, categorization and clinicopathological correlation of papulosquamous skin disorders.

 

Keywords: Histopathology; Lichenplanus; Papulosquamous Disorders; Psoriasis; Skin. 


Corresponding Author : M. Vijaya Lakshmi, Assistant Professor, Dept. of Pathology, Narayana Medical College, Nellore, Andhra Pradesh 524003, India.