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Indian Journal of Pathology: Research and Practice

Volume  5, Issue 2, May-Aug 2016, Pages 171-176
 

Original Article

Spectrum of Endometrial Hyperplasia in Abnormal Uterine Bleeding: A Descriptive Study in Tertiary Care Hospital Over 2 Years

Rajshri P. Damle*, Kishor H. Suryawanshi**, Nandkumar V. Dravid***, Rajeshwari Kumbhar****, Arundhati S. Gadre*****

*Associate Professor, ** Associate Professor, *** Professor and Head of Department, **** Assistant Professor, ***** Assistant Lecturer, A.C.P.M.Medical College, Department of Pathology, Dhule, Maharashtra, India

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.5216.17

Abstract

 Background: Unopposed estrogenic stimulation either due to exogenous or endogenous source is responsible for endometrial hyperplasia and is rare in women under the age of 30 years with an increasing incidence with age. Endometrial hyperplasia is a distinct clinical and pathologic entity and very closely related with abnormal uterine bleeding. Abnormal uterine bleeding is a relatively common gynecological condition that affects women in adolescent and perimenopausal age group due to anovulatory cycles or irregular maturation of follicles. Objectives: 1. To study the clinicopathological spectrum of endometrial hyperplasia in abnormal uterine bleeding above 40 years of age group. 2) To analyze the different patterns of endometrial hyperplasia and classify them according to WHO classification. Methods: The prospective study included 105 cases who histopathologically diagnosed various patterns of endometrial hyperplasia in patients of abnormal uterine bleeding above 40 years of age over the period of 2 years. The detailed clinical history was obtained. Specimens were routinely processed and H & E stained slides were studied. Result: A total of 105 cases of endometrial hyperplasia were studied. The most common age group presenting with endometrial hyperplasia was 4050 years (74.28%) and most common presenting complaint was menorrhagia (72.38%).The commonest pattern was simple hyperplasia without atypia (77.14% ) followed by complex hyperplasia without atypia. Conclusion: Endometrial hyperplasia is a common condition and usually associated with abnormal uterine bleeding above the age of 40 years. So it deserves special attention because of its relationship of progression to endometrial carcinoma. Early recognition and histopathological work up can prevent disease progression.

Keywords: Abnormal Uterine Bleeding; Endometrial Hyperplasia; Menorrhagia.


Corresponding Author : Rajshri P. Damle*