Introduction: West Nile Virus infection is a selflimited illness that can cause neuro-invasive illness including encephalitis & meningitis. Problem Statement: The first isolate of West Nile Virus was found in 1937 in Uganda. Recently in March 2019, a 7 year old boy was detected of West Nile Fever in Kerala’s Malappuram district who died of cardiac arrest following the complications. Prevention and control: One of the most efficient method of preventing West Nile infection is to raise awareness of risk factors among people and educate them about what steps they can take to reduce their exposure to the virus.

Keywords: West Nile Fever; Epidemic; India; Re-emerging Threat; Prevention.