Aim: The aim of the study was to find out the effectiveness of Occupational Therapy Program for patients with depression. Objectives: To find out the level of Depression for patients with depressive episode. To reduce the level of the Depression. To educate and train the ADL skills (Activities of Daily Living) for patients with Depressive episode. Methods: Ten patients with depressive episode for both male and female patients were selected for this study. All patients were screened by Beck Depression Inventory (BDI), was used for the objective measurement of patient’s Depression level. The pre and post therapy values were statistically analyzed on the effect of Occupational Therapy intervention for patients with depression. Result: The statistical analysis of Beck Depression Inventory (BDI) pre-treatment Mean value is 33.9 SD 1.3203 and post-treatment Mean value is 17.6, S.D 0.52068, t-test value of BDIs is 11.48444 and p value is < .00001. This statistical analysis shows that, there is significant difference between pre and post-therapy values of Beck Depression Scale score. Hence, it is suggested that, the level of Depression were reduced and the ADL skills were trained for patients with depression. Conclusion: Occupational Therapy can be used effectively as one of the most important; interventions to reduce the level of depression and to train as well make them independent in their activities of daily living. Hence, it is recommended that, the Occupational Therapist plays pivotal role in treating patients with depression. Psychiatrist, clinical psychologist and other health care professional may consider these interventions when dealing patients with depression.

Keywords: Depression; Occupational Therapy; Beck Depression Inventory (BDI); Activities of Daily Living; World Health Organization (WHO); National Institute of Mental Health (NIMH); Centers for Disease Control and Prevention (CDC).