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Indian Journal of Dental Education

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Indian Journal of Dental Education

Volume 11, Issue 2, April-June 2018, Pages 63-68

Review Article

Bone Morphogenic Protein: A Short Reveiw

Prachi Nayak1, Himanshu Singh2, Sushruth Nayak3

1Reader 2Oral Pathologist 3Professor, Department of Oral Pathology & Microbiology Maharishi Markandeshwar College of Dental Sciences and Research, Mullana, Ambala, Haryana 133207, India.

Open Access: View PDF

DOI: https://dx.doi.org/10.21088/ijde.0974.6099.11218.5

Abstract

Bone morphogenic protein (BMP) was first observed by Marshall Urist. Bmp is effective in the process of osteoinduction. BMP belongs to transforming growth factor-b superfamily. BMP is expressed in various oral lesions like osteosarcoma, malignant fibrous histiocytoma and fibrous dysplasia. The BMP’s play an important role in cell growth, its differentiation, apoptosis, preservation of joint integrity, vascular remodeling as well as commencement of fracture healing. The article is aimed at discussing various types of BMP’s, their functions, molecular characteristics and their role in various oral lesions.

Keywords: Bone Morphogenic Protein; Molecular Characteristics; Oral Lesions.

Corresponding Author : Prachi Nayak, Reader, Department of Oral Pathology & Microbiology, Maharishi Markandeshwar College of Dental Sciences and Research, Mullana, Ambala, Haryana 133207, India.