Introduction: cardiovascular  diseases (CVD) are the leading cause of morbidity and mortality across the world. Postmenopausal women may have an increased risk of CVD. Vitamin-D (Vit-D) is believed to have an important role in the progression of CVD. Hence the study was undertaken to assess the link between Vit-D and CVD among postmenopausal Kerala population.

Materials and Methods: A crosssectional study was undertaken in 149 postmenopausal women. Demographic parameters were collected by using a questionnaire. Blood samples were collected and Vit-D status of all volunteers was estimated. The sample population was further grouped into three based on the Vit-D status as Vit-D deficient, insufficient and normal groups. Other parameters such as blood glucose, blood pressure, TC, TG, HDL, and LDL were measured and recorded. The result was analyzed by using appropriate statistics.

Result: There was a significant difference in the biomarkers of CVD between the test groups. The one way ANOVA between the groups showed a significant difference (p 0.05) in body weight, FBS, HDL, and TG. The Person correlation test indicated a negative correlation between Vit-D with SBP, LDL, ApoB, hsCRP and Lp-PLA2. Whereas a positive correlation was noted with Apo-A1 levels.

Conclusion: The result of the present study revealed that there is a significant association between Vit-D status and risk for CVD in the postmenopausal women of Kerala population. The study could reveal the elevated levels of conventional and specific biomarkers for cardiovascular risk. 

Keywords: Postmenopausal Women; Vitamin D Status; Cardiovascular Risk;
Kerala Population.