AbstractObjective: To compare the onset and duration of sensory and motor block, haemodynamic responses, side effects associated with administration of intrathecal isobaric levobupivacaine (0.5%) and isobaric ropivacaine(0.75%) for inguinal hernioplasty. Place and Duration of Study: Rajah Muthaih Medical College, Chidambaram, 2016-17. Methodology: After obtaining approval from institutional ethics committee and written informed consent from all patients, a randomized controlled double blinded clinical trial was conducted on 50 ASA 1 and 2 adult patients undergoing elective inguinal hernioplasty. Patients were randomly allocated into two groups, group L and group R of 25 each. Patients in group L were to receive isobaric levobupivacaine 0.5% and group R 0.75% ropivacaine. Haemodynamic variables (heart rate, systolic and diastolic BP) and onset and duration of sensory and motor block, sensory regression time were recorded and compared.