Objective: Detrusor Overactivity (DO) was evaluated in patients with lower urinary tract symptoms due to benign prostatic hyperplasia with storage symptoms. Materials and Methods: A total of 258 men with a mean age 60.4±8.4 years who were admitted in our center between August 2013 and September 2015 with Lower Urinary Tract Symptoms (LUTS) having BPH. These patients were divided into two groups. Group1 (n=216) who had predominant obstructive voiding symptoms. Group2 (n=42) had both storage and voiding symptoms. Invasive urodynamics, including filling and voiding cystometry, was done with pressure flow analysis according to the Schäfer nomogram in Group2 patients. The relative contribution of bladder dysfunction to male LUTS, with a particular emphasis to storage symptoms that characterize overactive bladder was noted. Results: Of the 258 patients, 42 (16.3%) had idiopathic or neurogenic detrusor overactivity significantly affect patient symptom score and quality of life. Moreover, bladder dysfunction was significantly affected with the degree of obstruction with both storage and voiding symptoms as measured by the maximum flow rate, postvoid residual urine, and prostate volume and Schäfer grade of obstruction. Conclusion: DO with severe degree of bladder outlet obstruction in patients with storage symptoms is pathophysiologically the same as idiopathic or neurogenic.

Keywords: Overactive Bladder; Lower Urinary Tract Symptoms; Benign Prostate Hyperplasia.