The odontogenic keratocyst (OKC) is a commonly encountered developmental cyst of considerable importance because of its potential for aggressive clinical behavior and recurrence. Also, it may be a component of the nevoid–basal cell carcinoma (Gorlin) syndrome. Histologic features of OKC are pathognomonic. The common site of involvement is the mandibular ramus region but this case represents odontogenic keratocyst involving the mandibular anterior region. Most odontogenic keratocyst (60%) arise from dental lamina rests or from the basal cells of oral epithelium and are thus primordial-origin odontogenic keratocysts. The remaining 40% arise from the reduced enamel epithelium of the dental follicle and are thus dentigerous-origin odontogenic keratocysts.

Keywords: Corrugated parakeratinized epithelium; Mandibular anterior region; Odontogenic Keratocyst.