The purpose of the study was to assess the knowledge and attitude among post menopausal women of medical profession regarding hormonal replacement therapy. The Research Approach used was Survey Approach, with a Descriptive Design. The Setting of the Study was at areas of Panavoor Primary Health Centre, Trivandrum, among Post menopausal women under medical profession. There were 100 Samples selected by means of Purposive sampling. The tool used for Data Collection was structured questionnaire and 5 point Likert scale by Self Administration Method. The data were analysed using descriptive and inferential statistics. The overall mean and standard deviation of knowledge scores were 22.37 and 1.119 respectively whereas the overall mean and the standard deviation of attitude scores were 84.47 and 3.228 respectively.

Keywords: Assess; Knowledge; Attitude; Menopause; Post-Menopausal Women Hormonal Replacement Therapy.