Background and Objective: Incidence of preeclampsia in India is reported to be 8-10% of pregnancies. It is a non-convulsive form of hypertensive disorder of pregnancy. The present study has been undertaken to estimate and compare the serum values of calcium, uric acid, triglycerides, total cholesterol HDL-C and LDL-C between l non pregnant healthy women, normotensive pregnant women and pre-eclamptic women. Materials and Methods: Study includes 120 women divided into three groups. Estimation of serum calcium, uric acid, triglycerides, total-cholesterol and HDL-C were analyzed by O-CresolphthaleinComplexone , Modified Trinder Peroxidase, CHOD-PAP and Phosphotungstic acid precipitation method, using Erba Chem-5 plus semi-autoanalyser. Results: Mean serum calcium and HDL-C levels were significantly decreased in group-C and group-B in comparison to group-I,p<0.05. The mean serum concentration of uric acid in pre-eclamptic pregnant women (group-C) was significantly elevated than normotensive pregnant women (group-B) cases and healthy non-pregnant women (group-A). The mean triglyceride, and LDL-C levels were significantly increased in group-C as compared to group-B, p<0.05. But there was no difference in the mean values of total-cholesterol between cases (group-B and groupC) and control (group-A), p>0.05. Conclusion: Women having pre-eclampsia had low levels of serum calcium, elevated the serum uric acid and disturbed lipid profile. These levels may have cause and effect relationship with these disorders.
Keywords: Pregnancy; Pre-Eclampsia; Calcium; Uric Acid; Lipid Profile; Women.