Molluscum contagiosum (MC) is a self-limiting cutaneous viral disease caused by a double stranded DNA virus belonging to pox viridae family. The lesions are highly contagious and present as elevated pearl like papules with characteristic central umbilication. It can affect children, sexually active adults and immunocompromised individual.1 It is classically a clinical diagnosis and does not pose difficulty in diagnosis unless the presentation is atypical. Thus, the cytological features of MC are rarely described and reported, more so with Tzanck smear.1 We are presenting a case of MC in a 27- year- old male which was diagnosed on Tzanck smear. We are presenting this case to emphasize on rapid diagnosis of MC using Tzanck smear.