AbstractAmlodipine overdose is scarcely reported from India, though rare but associated with high mortality. It can lead profound refractory hypotension and shock leading to end organ damage. Management involves early and aggressive measures and calcium in large doses to overcome competitive blockade, hyperinsulinemiaeugycemic therapy, along with some rescue therapies tried in anectodal reports. We report one such case of amlodipine overdose and was successfully managed.