Diabetic foot ulcers (DFU) develop as a complication of diabetes mellitus and represent  significant morbidity, mortality, and healthcare costs. Thorough debridement, wound dressings,  offloading, vascular assessment, infection control, glycemic control, and a multidisciplinary approach are needed. Along with this, newer agents such as nanomolecules and nanodrug  delivery system are emerging. This overview article discusses recent trends in DFU and its management.