Mononeuropathy in children and adolescents may be due to post-infectious, infectious, metabolic-endocrine, injuries, pressure from outside or at compression sites. Otherwise it may be idiopathic. We describe here- in an adolescent girl with history of substance abuse who presented with  pressure induced mononeuropathy of distal sciatic nerve about 6 months after her deaddiction
and rehabilitation. This followed her being in a friendly gathering at one of her friends' house  where she spent 2 hours in cross-legged posture. She had an acute onset left sided foot drop  immediately after standing up from the prolonged cross-legged posture with inability to raise  her forefoot and numbness over whole leg and foot with inability to stand without support.  Electrodiagnostic study of her lower limbs revealed axonal motor and sensory neuropathy of  peroneal (fibular) and tibial nerves. She was treated conservatively with physical therapy and avoiding sitting cross-legged posture and a short course of steroid. She showed improvement  in 3 wks. Her follow up has been satisfactory so far.