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RFP Journal of ENT and Allied Sciences

Volume  8, Issue 2, July - December 2023, Pages 47-50
 

Case Report

Submucosal Globular Tongue Swelling: A Rare Presentation of Adenoid Cystic Carcinoma

Prince Handa1, Mehneet Sawhney2, Anmol Rattan Kath3, Nishtha Batra4

1,2Fellow, 3Consultant, Department   of Head and Neck Oncology, 4Consultant, Department of
Pathology, Homi Bhabha Cancer Hospital, Sangrur (A Unit of  Tata Memorial Centre), Sangrur 148001, Punjab, India.
 

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Abstract

Introduction: Adenoid cystic is an infrequent malignancy of the salivary glands. Some of its   unique features include slow growth, the tendency for perineural invasion, local recurrence, and the ability to metastasize. The mobile tongue's adenoid cystic carcinoma (ACC) is a rare reported case in the literature.  Report: We report a rare case of adenoid cystic carcinoma, in a 55-year-old female arising  in the dorsal and lateral aspect of tongue. Histopathology after complete excision of the mass  confirmed the diagnosis of adenoid cystic carcinoma. There has been no evidence of disease   following excision with tumour-free margins.  Discussion: The pathophysiology of ACC is an understudied area due to the condition's  rarity. Chromosomal abnormality and dysregulated MYB oncoprotein have to be thought to  play a key role in the pathophysiology and proliferation of ACC.  Conclusions: Adenoid cystic carcinoma of the tongueis exceedingly rare but should be  considered in the differential diagnosis in patients with tongue swelling. These tumours are  malignant and treatment requires surgical excision and neck dissectionfollowed by adjuvant  radiotherapy.
 


Keywords : Adenoid cystic carcinoma; Carcinoma tongue; Oral cavity; Perineural invasion; Lingual tumours.
Corresponding Author : Mehneet Sawhney,