Context: Disturbances in mineral metabolism are commonly seen in patients with chronic renal failure. But there are very few studies on their prevalence in Indian dialysis population. Aim: To know the prevalence of secondary hyperparathyroidism in patients with stage 5 chronic kidney disease on maintenance hemodialysis. Settings and Design: Hospital based cross sectional study. Methods and Material: This study was done on 85 patients undergoing maintenance hemodialysis for > six months. and data was collected between January 2018 and December 2018, for a period of one year.Patients were examined for clinical features of secondary hyperparathyroidism and serum calcium, phosphorus, alkaline phosphatase, 25 hydroxy vitamin D and intact parathyroid hormone levels were measured. Statistical analysis used: The data was analysed with SPSS using Descriptive statistics, Chi-square testand significance by p value. Results : Various mineral, bone abnormalities in our study population were as follows- hypercalcemia (5.88%), hypocalcemia (36.47%), hyperphosphatemia (30.59%), hypophosphatemia (28.24%), hyperparathyroidism (36.48%), hypoparathyroidism (10.59%), deficiency of vitamin D(52.94%) and insufficiency of vitamin D (20%). Conclusions: Prevalence rate of secondary hyperparathyroidism was 36% in our study and 40% had over suppresion of iPTH levels. One third of our patients had a risk of adynamic bone disease.

Keywords: Chronic kidney disease; Secondary hyperparathyroidism; hemodialysis.