AbstractChorangiomas are benign neoplastic lesions of the placenta and usually are a common incidental finding, but giant chorangiomas that measure more than 5cm in diameter are rare. Small chorangiomas typically do not cause detrimental consequences. But giant chorangiomas may lead to both fetal and maternal complications such as fetal congestive cardiac failure, fetal hydrops, polyhydramnios, preterm labor, and even intrauterine fetal demise. Here, we report a case of a primigravida at 22 weeks and three days of gestation presented with a giant placental chorangioma leading an adeversefetal outcome.