AbstractA study was conducted on eighteen SVVU T-17 grower pigs with similar body weights, and were divided into three groups with 6 pigs in each group for a period of 60 days to study the effect of inclusion of rice distillers dried grains with solubles (DDGS) and Mannan oligosaccharide (MOS) supplementation to the basal diet on serum biochemical parameters. The study revealed that among the biochemical parameters ALT, AST, Creatinine and Cholesterol exhibited significant decrease (P<0.05) in Mannan-oligosaccharides (MOS) supplemented group compared to other groups. Whereas, total protein and blood urea nitrogen (BUN) did not differ significantly (P>0.05) among the different groups. whereas in rice DDGS supplemented group there was no much observable effects on serum biochemical parameters in SVVU T17 crossbred pigs.