The Study was conducted using Quasi Experimental pre-test and post-test Control Group research design, among 60 patients (30 control group and 30 experimental group) from Osteoarthritis samples were selected using purposive sampling technique. Data was collected using demographic variables, Modified Lequence Observational checklist and numerical pain intensity rating scale was used to measure the pain level. Study findings reveals that post-test level of pain among experimental group it was found that the mean value was 3.2 and the standard deviation was 2.35, whereas in control group mean value is 5.93 and standard deviation was 2.63 and the‘t’ value was 7.01, it shows that there is significant reduction in post-test level of pain in experimental group than post-test level of pain in control group at p<0.05 level. It indicated that isometric exercises were effective in reducing the pain among osteoarthritis patients.