COVID 19 has change the entire healthcare delivery system time to time, various strains has been observed and different complication has been observed time to time in different age group. Similarly case presented here with refractory diarrhea and Transaminitis. COVID 19 is a deadly Pandemic and effecting people throughout the world. Whole world is looking for the varied option for treatment and the second wave has almost caused the lot of mortality and morbidity. No age group is spare of the COVID 19 manifestation from pediatric & Geriatric age group