Anesthetic and airway management of microstomia patients is challenging for anesthesiologists and requires special care and preparation during intubation and extubation. Back up plan with other airway management equipment’s should be available at hand before dealing with these patients, Decision of extubation is crucial and senior anesthetist should be available in the operating room. In case of prolonged surgery elective ventilation should be done in these cases. Keywords: Anesthetic; Difficult; airway; Post burn; One contract.