Background: Percutaneous renal surgery caused a revolution in the treatment of renal stone surgery.It is now considered the first line intervention for management of patients with asignificant stone burden. Percutaneous nephrolithotomy in the prone position allows better access to perform upper urinary tract endoscopy surgery with ability to clear the stones. This study represents a case series to evaluate how successful a standard percutaneous nephrolithotomy is, as a tool for clearance forrenal stones. Methodology: PCNL was carried out on 123 patients who were having renal stone size between 2 to 4cms from January 2014 to December 2017 at JJMMC, Davanagere, a tier 2 city in Karnataka. We have observed the site and number of the required access, the intra and postoperative complications. Results: The procedure was completed, using a single access tract in 110 patients, with the site of puncture being the lower calyx in 40 cases[ 36.36%], the posterior middle calyx in 60 cases[54.54%], 10 superior calyceal puncture (9%),Only in thirteen patients[ 10.5%], two access tracts (an upper and a lower calyceal) were required for completion. We had post op complications in 13 cases with 7 cases requiring ancillary procedures for stone clearance. Conclusion: Supine Percutaneous nephrolithotomy is a safe and successful procedure for the management of renal stones in terms of morbidity, convalescence, and cost replacing open surgical removal of renal calculi.

Keywords: Percutaneous Nephrolithotomy; Kidney; Renal Calculi; Horseshoe Kidney.