An explosion is defined as a violent, shattering action caused by a bomb. The main chemical ingredient of a bomb is the explosive – an endothermic substance which serves as a storehouse of energy. When this energy is suddenly released, in the confined space of the bomb, it causes a devastating effect, resulting in loss of lives and property. As compared to conventional crime scenes, explosion sites are more difficult to process. In many cases a building may have collapsed and the crime scene evidence may have become buried beneath the debris. A vital aspect of forensic investigation of bomb blasts is to establish the explosion seat. Equally important is to identify the type of chemical explosives used to commit the crime. This communication highlights the complications encountered in the management of explosion sites and the difficulties experienced in processing the evidence collected there from. The types of injuries which the victims of explosion suffer are also briefly described.