Central giant cell granuloma is a benign lesion which almost exclusively manifests in maxillofacial region. Usual site is anterior mandibular region. Radiographic features of this lesion closely resemble ameloblastoma and hyperparathyrodism. It is difficult to differentiate its histopathologic picture from that of hyperparathyrodism without co-relating clinically. This is a case report of central giant cell granuloma in body region of mandible along with its management and discussion (in literature). Giant cell lesions of the jaw comprises of an interesting and controversial group.1 Among these giant cell granuloma is commonly encountered lesion. Any swelling which is not painful, gradually increasing in size and vascular in appearance raises the possibility of presence of giant cell granuloma. The case of peripheral as well as central giant cell granulomas are extensively well documented in literature2 , and has been confirmed that 99% of giant cell tumor in jaws are giant cell granuloma. As it was presumed that it is an aftermath of trauma reparative word was frequently used (initially). In recent years term reparative has been deleted from original name given by Jaffe3 as it was found that lesion is basically destructive in nature rather than reparative.