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Indian Journal of Obstetrics and Gynecology

Volume  7, Issue 1, Jan-Mar 2019, Pages 35-43
 

Original Article

Compare the Efficacy of Rectal Misoprostol with Intravenous Oxytocin in Managing the third Stage of Labour

Mannapuram Padma

1Assistant Professor, Department of Gynaecology and Obstetrics, Government Medical College, Mahbubnagar, Telangana 509001, India.

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DOI: DOI: http://dx.doi.org/10.21088/ijog.2321.1636.7119.7

Abstract

Aim: To compare the efficacy and side effects of 800 micrograms rectal Misoprostol with intravenous oxytocin in managing the third stage of labour. Materials and methods: This study was done in 300 women undergoing full term vaginal delivery with or without episiotomy were enrolled to compare to efficacy and side effects of rectally administered Misoprostol with inj.oxytocin for management of III stage of labour. Study was done over a period 2 years, women enrolled and randomly distributed to two groups. 150 women in Group A received rectal Misoprostol and 150 women's in Group B received 10 IU IV oxytocin in drip. Results: Majority of subjects were between 21-26 years in both the groups. Majority of the subjects were primigravida 53% and 52% in Misoprostol group and oxytocin group respectively. Mean haemoglobin in two group was 8.86±1.05 gm/dI and 8.08±0.83 gm/dl in Misoprostol and oxytocin group 1-day postpartum. Mean PCV was 30.71±2.30 (Mean change=1.93±1.97) and 27.58±3.61 (Mean change = 3.77±4.4) respectively in misoprostol and oxytocin group. Duration of III stage in misoprostol group was 11.07±2.49 minutes compared to oxytocin group 11±3.93 minutes.5.33%, 2%, 4% and 2% had shivering, pain abdomen, temperature and diarrhea respectively in group A and 2% & 4.6% had shivering and fever respectively in Group B. All these were minor ailments subsided on their own without any intervention. No case of PPH was reported. Conclusions: Present study justify the use of per rectal misoprostol as an alternative to prophylactic injection oxytocin because of several advantages.

Keywords: Misoprostol, Postpartum haemorrhage, Oxytocin.


Corresponding Author : Mannapuram Padma, Assistant Professor, Department of Gynaecology and Obstetrics, Government Medical College, Mahbubnagar, Telangana 509001, India