AbstractIntroduction: Thyroid diseases are the commonest endocrine disorders affecting women of reproductive age group and hence constitute the commonest endocrine disorder in pregnancy also. Hyperthyroidism or hypothyroidism can influence the outcome for mother and fetus at all the stages of pregnancy. The aim of this study is to establish the prevalence and effect of thyroid disorder on pregnancy outcome. Materials and Methods: This study was a prospective study carried on 920 women coming for antenatal checkup in Adichunchunangiri Institute of Medical Sciences, B.G. Nagar, from October 2014 to September 2015. All women who were included in this study were followed up from 1114 weeks of pregnancy up to delivery for thyroid disorders and their outcome on pregnancy. Results: Totally about 8.69 % (80) of 920 antenatal patients were diagnosed as thyroid disorders. The most common thyroid disorder was subclinical hypothyroidism accounting to 4.13% and patients having overt hypothyroidism the most common complication was preeclampsia 30.76% (8/26), 38.46% (10/26) babies developed jaundice. Conclusion: TSH is the hallmark in detection of hypothyroid as well hyperthyroid, so TSH should be routine investigations done in all antenatal women in first trimester. If TSH values are abnormal then FT3, FT4 and TPOAb need to be checked. Gestational age specific reference intervals are of utmost importance for monitoring thyroxine replacement therapy in pregnant women.
Keywords: Thyroid Disease; Pregnancy; FetoMaternal Outcome; Prevalence .