Advertisement!
Author Information Pack
Editorial Board
Submit article
Special Issue
Editor's selection process
Join as Reviewer/Editor
List of Reviewer
Indexing Information
Most popular articles
Purchase Single Articles
Archive
Free Online Access
Current Issue
Recommend this journal to your library
Advertiser
Accepted Articles
Search Articles
Email Alerts
FAQ
Contact Us
Indian Journal of Obstetrics and Gynecology

Volume  8, Issue 1, January-March 2020, Pages 21-24
 

Original Article

Clinical and Radiological Features of Posterior Reversible Encephalopathy Syndrome in Patients with Antepartum Eclampsia

Meenakshi S Devarmani1, Neha Singh2

1Professor, 2Post Graduate Student, Department of Obstetrics and Gynaecology, Mahadevappa Rampure Medical College, Kalaburagi, Gulbarga, Karnataka 585105, India.

Choose an option to locate / access this Article:
60 days Access
Check if you have access through your login credentials.        PDF      |
|

Open Access: View PDF

DOI: http://dx.doi.org/10.21088/ijog.2321.1636.8120.3

Abstract

Objectives: Incidence of eclampsia in the western world is 1 in 2000 and 1 in 3448 pregnancies, but it is many times high in developing countries with incidence of 1.5% in India. Posterior Reversible Encephalopathy Syndrome (PRES) also known as reversible posterior leukoencephalopathy syndrome occurs in association with a number of causes, most commonly hypertension, pre-eclampsia/eclampsia and renal injury. Aim of the study was to find about the incidence of PRES in patients with antepartum eclampsia by brain imaging using MRI and MRV. Material and methods: It was a retrospective cohort study of all patients of antepartum eclampsia with PRES syndrome over a period of two years from 1st June 2017 to 31st July 2019 managed at Basaveshwar Teaching and General Hospital, attached to Mahadevappa Rampure Medical College, Kalaburagi, Karnataka, India. Results: A Total of 140 patients with antepartum eclampsia delivered at Basaveshwar Teaching and General Hospital, attached to Mahadevappa Rampure Medical College, Kalaburagi, Karnataka during the study period; that is between 1st June 2017 and 31st July 2019. Of these 14 patients had PRES with an incidence of 10% of all patients with antepartum eclampsia. The incidence was more in primigravidas (78%) than in multigravidas (22%). 10 patients were 20–25 age group, 13 presented with multiple seizure episodes. In 12 patients seizures were controlled only with MgSO4. Mode of delivery was by vaginal route in 5 patients. Perinatal mortality was seen in 5 patients. There was no maternal mortality in our study. Conclusion: Incidence of PRES was 10% amongst the patients delivered with antepartum eclampsia at Basaveshwar Teaching and General Hospital, Kalaburagi. Signs of imminent eclampsia headache, epigastric pain and blurring of vision were present in these patients. In the majority of the patients seizures were controlled with MgSO4 alone. MRI and MRV were the investigation of choice. Prognosis of PRES in patients with antepartum eclampsia was favorable.


Keywords : PRES; Antepartum eclampsia; MRI; MRV.
Corresponding Author : Meenakshi S Devarmani