Laser toning using low-fluence 1064-nm QSNY is being increasingly used to target photoaging and hyperpigmentation in darker skin types. However, sub-optimal response stemming from the use of low-fluences, as well as development of complications especially punctate leukoderma are also being increasingly reported with this approach. Since the development of the fractional- lasers, the fractional mode has been successfully incorporated with QS Nd: YAG (QSNY) laser (1064 nm) systems. Fractional mode lasers have the advantage of sparing certain areas in between the treated areas called microscopic treatment zones (MTZs), allowing for rapid healing, shorter recovery times, and less post-inflammatory complications. In this case series, we report our experience of a novel US-FDA approved fractional QSNY laser device Helios III in the treatment of various cutaneous lesions disorders in Indian patients including melanocytic nevi, atrophic scars, pigmented scars, laser hair reduction, reduction of white hair, melasma, and toe nail onychomycosis.

Keywords: Fractional Laser; Q-Switched; Nd:YAG; 1024 NM; Scars; Melasma; Hair Reduction.