AbstractBackground: Ischemic heart disease (IHD) and stroke constitute the
majority of CVD mortality in India (83%), with IHD being predominant.
Objectives: To correlate the level of Hs-crp with risk factors like age ,
hyperlipidemia , obesity and to correlate the level of Hs-CRP with
number of vessel involved and percentage of stenosis.
Material and Methods: This cross sectional study was conducted on patients admittedin the Intensive cardiac Care Unit of Karnataka Institute of MedicalSciences, Hubli between November 2015 – January 2017. A total numberof 110 patients were recruited for the study. Results: Out of the total 110cases 78(70.9%) were male patients and 32(29.1%) female patients. Mostof patients were in age group of 51-60 yrs (40%). 77 patients (70%) were obese BMI>25. 56(52.8%) were SVD,12(11.3%) were DVD,20(18.9%)were TVD, and 18(17%) had normal coronaries. There was significant difference in mean hsCRP with respect to vessel blocked distribution, higher was seen with TVD(6.4mg/l)>DVD(2.7md/l)>SVD(1.3mg/)>normalcoronaries(1.2mg/l) There was positive correlation between hscrp and LDL,TG, and significiant negative correlation with HDL. There was significiant negative correlation of hscrp with EF. Conclusion: It was concluded hsCRP correlates with cardiovascular risk factors like obesity, dyslipedimea. hscrp can predict the number of vessel involved
and indirectly severity of disease. hscrp and EF together could predict
severity of disease.
Keywords: Ischemic Heart Disease; Hs-CRP; Hyperlipidemia;
Obesity; Ejection Fraction.