Introduction: Placenta, which serves as a crucial foeto-maternal interface, is the central support organ for developing fetus, hence its abnormalities can have an impact on both maternal and fetal health. Abnormal placentations result in poor placental perfusion and placental insufficiency.USG of placenta is primarily directed toward determining the location of the placenta and identifying its abnormalities in later weeks of pregnancy. Aims & Objective: To determine the maternal outcome depending on second trimester placental location between 18-24 weeks and to determine whether it can be considered as a screening tool to predict these complications. Method: This retrospective study is conducted at ACPMMC Dhule. 200 pregnant women with singleton pregnancy, who delivered after 28 weeks of gestation during 1 year period, who had prior documentation of placental location on the basis of antenatal USG performed between 18-24 weeks were included. Placental position was then categorized as anterior, posterior, fundal, lateral and placenta previa. Association of placental location with maternal outcome was then noted. Result: Out of 200 women, the frequency of central placentation was 166 (82.8%), lateral placentation 32 (16.2%) and placenta previa was 2 (1%). Central placentation had an abnormal outcome in 77(46.3%) and lateral placentas with abnormal outcome were 18(57.2%). Abnormal maternal outcomes like Antepartum haemorrhage(APH) (23%), Pregnancy Induced Hypertension(PIH) (29%), Intrauterine Growth Restriction(IUGR) (16%), Preterm Birth(15%) were more in lateral placentation. Placenta Previa carried an increased risk of Postpartum haemorrhage(PPH) and Adherent placenta. Conclusion: In our study, there is a significant association between lateral placentation and abnormal pregnancy outcomes. Therefore, placental location by Ultrasound examination done in second trimester is used as non-invasive predictor in determining adverse maternal outcomes

Keywords: Placental location; Lateral location; Abnormal outcome; Maternal outcome; Second trimester; Ultrasound