Introduction/Context: Neoplasms of skin appendages are infrequently encountered in practice. Histopathology is the gold standard investigation for the final diagnosis. Aim of the Study: Approach to the diagnosis of skin adnexal tumors on the basis of histomorphological patterns and cell morphology. Materials and Methods: The present study is a retrospective study done in the department of pathology. All cases are collected from 2004–2018, total of 14 years retrospective study. Inclusion Criteria: All skin biopsy diagnosed as skin adnexal tumors. Exclusion Criteria: Inflammatory condition, inadequate biopsy, Cyst and tumor like lesions. Results: Total 90 cases of skin adnexal tumors were included in the present study. Out of 90 cases, 42 (47%) are male patients and 48 (53%) are female. According to histomorphological pattern, 78% have solid patterns, 17% have solid and cystic, and rest are cystic. As per cell morphology, basaloid cells forms predominant in skin adnexal tumors with 50% of cases. Discussion: In the present study, a new concept of histomorphological pattern is included, which is rarely studied. The histomorphological pattern is classified into solid, solid and cystic and predominant cystic pattern. Solid pattern constitutes 78% of adnexal tumors. It is predominantly seen in eccrine gland tumors like Eccrine spiradenoma, Eccrine hidradenoma. Cystic pattern is seen in 5% of adnexal tumors. It is seen in pilar tumors like pilomatrixom a,trichoepithelioma. Solid and cystic pattern is seen in 17% of adnexal tumors. It is seen in both eccrine, apocrine and pilar tumors. Conclusion: Hence, combining the histomorphological pattern and cellular morphology helps pathologist to diagnose with ease.

Keywords: Adnexal tumors; Basaloid; Clear cells; Solid pattern.