Advertisement!
Author Information Pack
Editorial Board
Submit article
Special Issue
Editor's selection process
Join as Reviewer/Editor
List of Reviewer
Indexing Information
Most popular articles
Purchase Single Articles
Archive
Free Online Access
Current Issue
Recommend this journal to your library
Advertiser
Accepted Articles
Search Articles
Email Alerts
FAQ
Contact Us
Indian Journal of Forensic Medicine and Pathology

Volume  12, Issue 2, April-June 2019, Pages 73-77
 

Original Article

Histopathological Spectrum of Fungal Infections in a Tertiary Care Hospital

Abilash Sasidharannair Chandrakumari1,5, Pammy Sinha2, Shree Lakshmi Devi Singaravelu3,5, Jaikumar S4

1Associate Professor, Dept of Pathology, 3Associate Professor, Dept of Pharmacology, Shri Sathya Sai Medical College & Research Institute Chennai, Tamil Nadu 603108, India. 2Professor & Head, Dept of Pathology, 4Professor, Dept of Pharmacology, Sri Lakshmi Narayana Institute of Medical Science Medical College & Hospital, Puducherry 605502, India. 5Research Scholar, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu 600126, India.

Choose an option to locate / access this Article:
60 days Access
Check if you have access through your login credentials.        PDF      |
|

Open Access: View PDF

DOI: DOI: http://dx.doi.org/10.21088/ijfmp.0974.3383.12219.4

Abstract

Context: Infections caused by funguses are increasing at a steady rate worldwide. Elderly individuals and who are at an immunocompromised state are at risk of developing this disease. Though fungal infections which either manifest as cutaneous or invasive type, Cutaneous lesions are very common. Fungal diseases are diagnosed usually by correlating the clinical findings with histopathology and confirmation is done based on culture. Aim: The current study was aimed at categorizing the spectrum of fungal infections diagnosed in the histopathology specimens and their distribution according to age, sex and site of involvement. Settings and Design: This was a cross sectional analysis, conducted over a period of one year from September 2016 to August 2017. Methods and Material: A total of 60 cases were enrolled in the study. Clinical findings inclusive of age and sex parameters were noted from hospital registrars. Specimens were fixed in formalin and processed under standard procedure protocols. Slides were prepared and stained with routine H & E stain; special stains like PAS and GMS stains were used wherever necessary. Statistical analysis used: Data analysis was using IBM Statistical Package for the Social Sciences Software version 21. Significance of the statistical tests at P value less than 0.05 was based on 95% confidence interval. Results: Out of 60 cases, 18 cases turned out to be positive for fungal infection. The mean age of the studied population was 49.11 years (SD 11.02). The male female ratio was found to be 0.8:1. The mean age of male population was found to be 53.375 years (SD 7.44), mean age of female population was 45.7 years (SD 12.54). The commonest fungal infection encountered in our study was Rhinosporidiosis. Conclusions: Histopathological examination provides reliable diagnosis in individuals with uncertain clinical findings of fungal infection.

Keywords: Immunocompromised; Cutaneous; Rhinosporidiosis; Histopathology; periodic acid– Schiff.


Corresponding Author : Abilash Sasidharannair Chandrakumari