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Indian Journal of Forensic Medicine and Pathology

Volume  14, Issue 3(Special Issue), July - September 2021, Pages 675-680


Review Article

Impact of Degradation of Blood Samples on RNA, DNA and HB: A Review
1Anjali Malik, 2Sally Lukose, 3Ishika Bhardwaj
1,3Assistant Professor, 2Professor, , School of Allied Health Sciences, Sharda University, Greater Noida, Uttar Pradesh 244001, India
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context: The collection of biological evidence from various crime scenes for identification purposes is an important task to achieve. Where different biological evidence serves as an important source of information, whole blood samples and bloodstains act as a prime source of identification. Blood samples are mostly found to be exposed to various environmental conditions, which results in the degradation of samples. It is quite inaccessible for forensic experts to re-evaluate the evidence and get the same outcomes as earlier because of storage conditions of the biological samples. Hence, the stability of nucleic acids and hemoglobin is very crucial. This study was conducted to present a review on the available facts of different storage conditions and temperatures on the stability of ribonucleic acid (RNA), deoxyribonucleic acid (DNA) and hemoglobin (Hb). The study also provides an outlook for ideal storage temperature and conditions for blood samples and appropriate preservation of same immediately after the collection from the crime scene

Corresponding Author : Anjali Malik