Background: Burn injuries constitute a major health concern with respect to morbidity and mortality. Burns are a very common injury, serious burn injuries are ex­cruciatingly painful and require special care to prevent infection and reduce the severity of scarring. Objectives: To determine the predominant bacterial pathogens in the burn wound infection with age, sex and cause of injury, and to know the antibiotics sensitivity profiles of the isolates obtained. Material & Method: Burn Patients admitted within 24 hours were included. Whereas Patients admitted after 24 hours were excluded. Two burn swabs were aseptically collected on admission before the start of antibiotics. One swab was subjected for gram staining and the other for culture. All specimens were inoculated on 5% blood agar and MacConkey agar and incubated. Isolated organisms were subjected for Antibiotic Susceptibility. Result: Maximum patients (50%) belonged to 21­ 40 years age group. and males 39 (65%) were predominant over Female as 21 (35%), Cause of burn in Maximum number of patients was fire burn 25 (41.6 %) Among single isolates Pseudomonas aeruginosa was leading (20.8%) followed by Acinetobacter baumannii (15.4%), staphylococcus aureus (14.1%) and Klebsiella pneumoniae (7.5%). Antibiotics susceptibility pattern of gram positive bacteria showed good sensitivity to Gentamycin, Linezolid, Vancomycin, Ciprofloxacin and Clindamycin. Antibiotics susceptibility pattern of gram Negative bacteria showed good sensitivity to Imipenem, Meropenem, Tobramycin, Amikacin, Kenamycin, Cefoperazone, and Tetracycline. Conclusion: Microbial colonization was present right from the time of admission in the majority of swabs. The commonest organism isolated was Pseudomonas Aeruginosa followed by Acinetobacter baumannii, staphylococcus aureus, Klebsiella pneumoniae, Enterobacter, Enterococcus species Escherichia coli, proteus mirabilis, CONS and Citrobacter species.

Keywords: Burn wounds, Invasive Infection, Pseudomonas Aeruginosa, Antibiotic Susceptibility.