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Ophthalmology and Allied Sciences

Volume  4, Issue 1, Jan-Apr 2018, Pages 17-21
 

Original Article

Clinical Presentation and outcome in Cases of Orbit Lymphoma: A Prospective Interventional Study

Hymavathi Bommisetti*, Rajitha Kondam**

*Assistant Professor, Department of Ophthalmology, Apollo Institute of Medical sciences and Research (AIMSR), Hyderabad, Telangana 500033, India. **Assistant Professor, Department of Ophthalmology, Malla Reddy Institute of Medical Sciences (MRIMS), Hyderabad, Telangana 500055, India.

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DOI: http://dx.doi.org/10.21088/oas.2454.7816.4118.3

Abstract

Context: The origin of orbital lymphoma can be variable. It may arise from conjunctiva or likely to arise from eyelid or may happen to arise from orbit or lacrimar glands. Diagnosis is most likely to be delayed as the clinical features are not very specific. Aims: To study clinical presentation and outcome in orbital lymphoma cases. Settings and Design: It was a Prospective Interventional Study carried out at Sarojini Devi Eye, Hospital, Hyderabad for a period of two years. Methods and Material: A total of 26 cases were included in the study. Only lymphoma orbit cases were included. Appropriate intervention was done depending upon the need i.e. stage, histological type, patient age and any other patient characteristics. Outcome was studied specific to the intervention carried out. Statistical Analysis: The data was entered in Microsoft Excel Worksheet and analyzed using proportions. Results: Male predominance was observed in present study i.e. males were 69% and females were 31%. Majority of the study participants had proptosis (23.8%) as main clinical presentation. About 19.23% had orbital & lid mass. Small Lymphocytic lymphomas were observed in 50% of the study participant, Diffuse mix small & large cell was seen in 30.7%, Diffuse large cell in 11.5% and Burkitt’s lymphoma in 7.6% of cases. Conclusion: Small Lymphocytic lymphoma was the most common orbit lymphoma found in the present study almost in half of the cases. Next most common histologic type was Diffuse mix small & large cell in about one third of the cases. Incisional biopsy & radiotherapy was the most commonly adopted intervention by us.

Keywords: Orbit; Lymphoma; Proptosis; Lid. 


Corresponding Author : Rajitha Kondam, Assistant Professor, Department of Ophthalmology, Malla Reddy Institute of Medical Sciences (MRIMS), Hyderabad, Telangana 500055, India.