AbstractAn imbalance of collagen synthesis and degradation is the most common cause of scarring. Onion extract inhibits fibroblast activity, which helps to reduce scar formation. Despite the fact that onion extract is used in a variety of commercial products, the precise molecular mechanisms by which onion extract reduces scar development in the skin are yet unknown. The aim of this study is to evaluate the effectiveness of onion extract gel in improving the scar. Keyword: Scar reduction, Onion extract gel.