Hylocereusundatus is the most widely cultivated vine cactus in the Cactaceae family, with native populations in Mexico and America. It is commonly known as "dragon fruit" or "pitaya" in the United States. In Malaysia, it is also known as "Buahnaga," which means dragon fruit. Aside from their appealing color, Hylocereusundatus fruits are prized around the world for their high content of polyphenolic components and antioxidant activity. Scientists have found that a wide range of phytochemicals, such as betalains, polyphenolic compounds, and carotenoids, protect against oxidant stress in the body and keep the right balance between antioxidants and oxidants to improve human health.The goal of this review's conclusion is to impart an understanding of Hylocereusundatus and its functional phytochemicals, as well as implications for its potential health benefits in the context of future research and application. More environmentally friendly antioxidant and antibacterial agents were proposed, which are important in the sectors of healthcare, food processing, nutraceuticals, and cosmeceuticals. To grow the global market for dragon fruit, experts will collaborate to enhance the importance of this fruit to worldwide cultivars. In the 1990s, dragon fruit became trendy in India. Agriculturists favored it for its low input costs and high profitability