Cystic lesion of bone can occur in any bone at any age/sex. and often are asymptomatic or may easily be 
confused with other bone lesions. Many of them typically resolve after skeletal maturity but some can result in 
pathologic fractures or local recurrence. In some lesions the danger of biopsy or other surgery may outweigh any 
benefit. So precise diagnosis is needed to prevent over/under treatment of lesions.
Keywords: Cyst of bone; Simple bone cyst; Aneurismal bone cyst; Intra-osseous ganglion cyst; Subchondral cyst.
Key Message: Not all bone cysts require treatment, in some lesions the danger of biopsy or other surgery may 
outweigh any benefit as they are painful/ fast growing / large /cause a fracture. Specific treatments are determined 
based on size of the cyst, strength of the bone, medical history, extent of the disease, activity level and the symptoms 
an individual is experiencing, and tolerance for specific medications, procedures, or therapies.