Abstract Introduction: It is imperative for an anaesthetist to know the adverse effects of shivering and hypothermia on human body which may occur when the patients are under anesthesia, so that timely treatment can be provided. Aim: To compare tramadol and dexmedetomidine in the treatment of shivering after spinal anesthesia. Materials and Methods: This was a randomized, prospective study in which 80 patients posted for elective surgeries given spinal anesthesia who developed shivering were included in the study. Results: The incidence of shivering was 40% in our study. The difference in the time interval between administration of drug after the onset of shivering and cessation of shivering was significantly shorter in the dexmedetomidine group when compared to the tramadol group. Changes in Heart rate, body temperature, mean blood pressure are not significant in our study in both groups. Nausea and vomiting observed in tramadol group, and not in the dexmedetomidine group. Conclusion: Dexmedetomidine can be a substituent to tramadol for cessation of post spinal anesthesia shivering.